TY - BOOK AU - Ibram Amin Fouad Ibrahim AU - Nadia Mohamed Sharaf , AU - Nesrine Salah Eldin , AU - Ragwa Mansour Abdelghany , TI - Role of thymoquinone against glutamate induced neurotoxicity in male albino rats / PY - 2016/// CY - Cairo : PB - Ibram Amin Fouad Ibrahim , KW - Alzheimer's disease (AD) KW - Male albino rats KW - Thymoquinone against glutamate N1 - Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology N2 - Alzheimer's disease (AD) is the most common neurodegenerative disease and is considered to be the leading cause of dementia in the western countries. Excitotoxicity have been implicated in the pathogenesis of several neurodegenerative disease including AD. Exposure to L-glutamic acid (GIu) excitatory neurotransmitter increases the activity of glutaminergic system & excitotoxicity. ER -