TY - GEN AU - Lamia Ezzat Mansour AU - Magdy Amin , AU - Salwa Rasmy , TI - Enhancement of biodegradation of aromatic compounds by using mixed culture and / or by immobilization / PY - 2006/// CY - Cairo : PB - Lamia Ezzat Mansour , KW - Biodegradation KW - Culture KW - Enhancement N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology; Issued also as CD N2 - P - Nitrophenol has been listed as a priority pollutant by the United States Environmental Protection AgencyIn this study isolates capable of utilizing PNP as a sole source of carbon were isolatedDegradation of PNP by the isolated strains was affected by : PNP concentration , inoculum size , agitation , pH and temperatureThe degradation of PNP appeared faster and open ended when the pH was maintained at 7The reaction was shown to be inducible and stopped in the presence of streptomycin and was haltedAll isolates were found to bear the common plasmid , which is presumed to be responsible for carrying genes involved in PNP degradation in these strainsImmobilization of bacteria made the biodegradation rates much faster than those occurring in conventional waste treatment systemsHPLC analysis indicated that the pathway for biodegradation of PNP involves the initial removal of the nitro group as nitrite and formation of HydroquinoneHydroquinone is converted to ? - ketoadipic acid via - hydroxymuconic semialdehyde and maleylacetic acid ER -