Synthesis and biological activity of some new thiazoles, thiadizoles and fused azolopyrimidine /
تشيد و النشاط البيولوجى لبعض الثيازولات و الثياديازولات وازولات البريميدين المدمجه الجديده
Esraa Mohamed Abdelfatah ; Supervised Abdou Osman Abdelhamid , Hamed Abdelreheem Ead
- Cairo : Esraa Mohamed Abdelfatah , 2017
- 197 P. ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
2-bromo-1-(5-methyl-1-(p-tolyl)-1H-1,2,3-triazol-4-yl) ethanone and 5- acetyl-4-methyl-2-(phenylamino)thiophene-3-carboxylate were used for the synthesis of several heterocyclic compounds as: 1,3,4-thiadiazoles, thiazoles, unsymmetericl azines, triazolo[3,4-a]pyrimidines, coumarines, 1,3,4-selenadi-azoles, [1,3,4] thiadiazolo [3,2-a]quinazolin-5-one, 1,3,4-thiadiazines, 3a,6a- dihydropyrrolo [3,4-c] pyrazolo-4,6(1H,5H)-dione, pyrazoles and pyrazolo[3,4- d]pyridazines. All the newly synthesized compounds were elucidated via elemental analysis, spectral data (IR, 1H NMR and MS) and alternative synthetic routes whenever possible. The newly synthesized compounds were screen test against microorganism