TY  - BOOK
AU  - Doaa Abdallah Zaky 
AU  - Dalaal Moustafa Abdallah , 
AU  - Muhammad Yusuf Alshorbagy , 
AU  - Noha Nagah Nassar , 
TI  - Modulation of intestinal gut barrier permeability by dipeptidyl peptidase IV inhibition in a model of rat septicemia / 
PY  - 2017///
CY  - Cairo : 
PB  - Doaa Abdallah Zaky B.Pharm , 
KW  - Adherens junctions
KW  - Oxidative stress
KW  - Vildagliptin
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy- Department of Pharmacology and Toxicology; Issued also as CD
N2  - BThe preferential role of the underlying PI3K/Akt (PKB) axis in triggering enterocytic proliferation/differentiation signaling and AJ assembly is still controversial. The involvement of CD26/DPP-IV in obstructive jaundice (OJ)-induced sepsis has not been yet reported VLD3/10/30 dose dependently modulated CD26/DPP-IV, GLP-1, IGF-1, PI3K, pS473-Akt, pS9-GSK-3Ý, pS133-CREB, and CD1. VLD3/10 increased E-cadherin and NPSH, however, they reduced pY654-Ý-catenin, portal and aortic endotoxin, NF-mB, TNF-Ü, MPO, TBARS, subepithelial/pericryptal and submucosal collagen deposition as well as vimentin immunoreactivity, effects that were quite opposed with VLD30
UR  - http://172.23.153.220/th.pdf
ER  -