TY  - BOOK
AU  - Hany Mohamed Ahmed
AU  - Ahmed Salah Eldin Hassan , 
AU  - Amr mahmoud Safwat , 
AU  - Mohamed Ahmed Elbeltagy , 
TI  - Management of fourth ventricular ependymomas / 
PY  - 2017///
CY  - Cairo : 
PB  - Hany Mohamed Ahmed , 
KW  - Extent of resection
KW  - Fourth ventricular ependymoma
KW  - Outcome
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurosurgery; Issued also as CD
N2  - Background: Ependymomas are rare neuroepithelial tumors which may arise anywhere along the ventricular system. Tumors arising in the 4th ventricle present unique challenges. Complete tumor resection favors prolonged survival, but may result in inadvertent injury of surrounding neural structures. Objective: to study clinical presentation, pathology, methods of investigations, operative techniques, complications of management of 4th ventricular ependymomas and eventually prognosis. Methods: This study was conducted upon forty patients with fourth ventricular ependymoma  with variable ages at the time of diagnosis, admitted and managed at the Neurosurgery Department, at Kasr AL Ainy Hospital and Children{u2019}s  Cancer  Hospital-Egypt  (CCHE-57357) between September 2015 and February 2017.Results: Total tumor excision was accomplished in 25 (62.5%) cases , near total resection in 5 (12.5%) cases, subtotal resection in 10(25%) cases. Pseudomenigocele occurred in 6 (15%) patients. Cerebellar mutism occurred in 4 (10%)  patients. Bulbar manifestations was present in 5 (12%) cases.Tumor recurrence occurred in 4 (10%) patients during the follow-up period. Clinical outcome 3 weeks after surgery was excellent and good in 32 (80%) cases, fair and poor  in 7 (17.5%) and there was one post operative mortality. Conclusion: Fourth ventricular ependymoma  is a surgically treated disease. Extent of resection is considered the most important factor affecting prognosis of fourth ventricular ependymomas. Nevertheless, brain stem invasion and histopathological grade are also considered  important factors affecting the outcome and prognosis
ER  -