Heba Ahmed Ramadan Basuny <br/><br/>
Expression of activated molecules on CD5+B cells in autoimmune hemolytic anemia /  
 بمرضى الأنيميا التكسيرية بالدم CD5+B دراسه وجود الجزيئات النشطة المتكونة على الخلايا الليمفاوية  
Heba Ahmed Ramadan Basuny ; Supervised Zakarya Ismail , Hend Nabil Ellithy , Walaa Abdelfattah Attya 
 - Cairo :   Heba Ahmed Ramadan Basuny ,   2017 
 - 82 P. :   charts , facsimiles ;   25cm  
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine 
<br/><br/> Autoimmune Hemolytic Anemia (AIHA) is characterized by shortened red blood cell (RBC) survival and the presence of autoantibodies directed against autologous RBCs (Petz et al., 2004). Evan's Syndrome is a combination between AIHA and Idiopathic or immune Thrombocytopenic purpura (ITP). B lymphocytes play important roles in the pathogenesis of AIHA/Evan's syndrome.  Recent studies have shown that CD5+B lymphocytes are associated with immune-related cytopenia and induction of apoptosis of CD5+b lymphocytes and down-regulation of activity of CD5+b lymphocytes can relieve this disease (Limin et al., 2005). In our study we investigate the expression of activation molecules on CD5+b lymphocytes in peripheral blood of autoimmune hemolytic anemia (AIHA)/Evan's patients. Expression of activated molecules on CD5+b lymphocytes (CD86, CD69, HLA-DR) was performed using flow cytometry (Petz et al., 2004)  
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<br/><br/><label>Subjects--Index Terms: </label>CD5+B  HLA-DR  RBC