Esraa Osama Abdelaziz Mostafa <br/><br/>
Effect of thymoquinone on Ü7 nicotinic acetylcholine receptor in LPS- induced neuroinflammatory Alzheimer's disease rat model /  
Esrss Osama Abdelaziz Mostafa ; Supervised Ola Heikal , Lobna Abdelaal Kassem  
 - Cairo :   Esrss Osama Abdelaziz Mostafa ,   2017 
 - 139 Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and toxicology 
<br/><br/> Alzheimer's disease (AD) is a neurodegenerative disorder resulting from the loss of cholinergic nerurons in the brain. It has been reported that Ü7 nicotinic acetylcholine receptors(Ü7 nAChRs) play an important role in cognitive processes representing a durg target for treating congnitive deficits. Ü7 nAChRs agonists cause memory enhancement through phosphorylation of cAMP response element binding protein (CREB)