TY  - BOOK
AU  - Fatma Ahmed Shalaby
AU  - Ali Mohamed Yehia , 
AU  - Laila Elsayed Abdelfatah , 
AU  - Lories Ibrahim Bebawy , 
TI  - Analytical study of some pharmaceutical nitrogenated cyclic compounds / 
PY  - 2017///
CY  - Cairo : 
PB  - Fatma Ahmed Shalaby , 
KW  - Aprepitant
KW  - TLC-densitometry
KW  - Zafirlukast
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD
N2  - This work is concerned with stability indicating methods for determination of some drugs containing cyclic nitrogen including; zafirlukast (ZAF), aprepitant (APR). In this thesis different analytical techniques were adopted, namely, TLC-densitometric, spectrophotometric, spectrofluorimetric, chemometric, liquid chromatography, for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and dosage forms. In part I; general introduction and literature review of ZAF and APR were described. In part II; different analytical methods were described for the determination of ZAF in presence of its alkaline degradates. Including; TLC-densitometry, second derivative (D2) spectrophotometry, specerofluorimetry, colorimetry. In part III; different analytical methods were described for the determination of APR in presence of its acid degradates. Including; TLC-densitometry, HPLC method, chemometry
UR  - http://172.23.153.220/th.pdf
ER  -