TY - BOOK AU - Nadine Medhat George Benyamin AU - Hassan Y. Aboulenein , AU - Lamia Ahmed Shihata , AU - Rasha Sayed Hanafi , TI - Determination of the design space of chiral HPLC separations on chirobiotic T stationary phase / PY - 2017/// CY - Cairo : PB - Nadine Medhat George Benyamin , N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry N2 - The integration of QbD approach into development of chiral HPLC method for the determination of the desgin space of separation of chiral durgs is a mandatory request by the food and drug Administration and the International conference on harmonzation guidelines presently . The current study aims to determine the design space of the enantiomeric separation of three beta-adrenergic blockers ; atenolol , metoprolol and pindolol on Chirobiotic T column in polar ionic mode with the aid MINITABĀ® statistical software UR - http://172.23.153.220/th.pdf ER -