TY - BOOK AU - Liza Samir Samy Botros AU - Darius P. Zlotos , TI - Novel strychnine dimers as bivalent ligands targeting glycine receptors / PY - 2017/// CY - Cairo : PB - Liza Samir Samy Botros , N1 - Thesis (M.Sc.) - German University - Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry N2 - Strychnine in the major alkaloid from the seeds of Strychnos nux-vomica and strychnos ignati. As a natural product, its structure has been optimized for strong interactions with biological macromolecules through evolutionary selection. Its most pronounced pharmacological action is an antagonistic activity at glycine receptors (GlyRs) UR - http://172.23.153.220/th.pdf ER -