Sarah Ehab Edward Riad Asaad

Eqigenetic targeting of the host surface / Junctional proteines : An approach intended to inhibit HCV entry into hepatocytes / Sarah Ehab Edward Riad Asaad ; Supervised Ahmed Ihab , Gamal Esmat , Ashraf Abadi - Cairo : Sarah Ehab Edward Riad Asaad , 2016 - 137 Leaves : charts , facsimiles ; 30cm

Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology

HCV entry is an a highly orchestrated process involving a complex interplay between viral and host molecules. Initial attacment of the virus to non-specific entry factors recruits the virus for post binding interactions with host receptors, wherein the viral E2 interacts with CD81 receptor.