TY  - BOOK
AU  - Rowaida Adel Abdelhamid Hassan 
AU  - Ashraf H. Abadi , 
AU  - Mohammed Abdelhalim , 
TI  - Synthesis of Novel Heterocycle derivatives as potential phosphodiesterase inhibitors and anticancer / 
PY  - 2017///
CY  - Cairo : 
PB  - Rowaida Adel Abdelhamid Hassan , 
KW  - Anticancer
KW  - Cyclicn nucleotide phosphodiesterase (PDEs)
KW  - Phosphodiesterase inhibitors
N1  - Thesis (M.Sc.) - German University - Faculty of  Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
N2  - Cyclicn nucleotide phosphodiesterase (PDEs) are promising targets for pharmacological ontervention. The presence of multiple PDE genes, diversity of the isoforms produced from each gene, selective tissue and cellular expression of the isoforms compartmentation within cells, and an array of conformations of PDE proteins are some of the properties that challenge the development of drugs that target these enzymes
UR  - http://172.23.153.220/th.pdf
ER  -