Mohamed Samir Sayed <br/><br/>
The role of platelet rich plasma (PRP) in femoral bone defect healing in dogs :   An experimental study /  
 دراسه  دور البلازما الغنية بالصفائح الدموية فى التئام قصور عظمة الفخذ فى الكلاب :   دراسه تجريبية 
Mohamed Samir Sayed ; Supervised Ahmed Sayed Ahmed , Elham Abdelgawad Hassan , Mokhtar Hanafy Gad 
 - Cairo :   Mohamed Samir Sayed ,   2017 
 - 104 P. :   photographs ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Surgery, Anesthesiology and Radiology 
<br/><br/> To evaluate the effect of autologous platelet rich plasma (PRP) for healing of femoral bone defect in dogs. Twenty four adult mongrel dogs was used in this study, a 2-cm cortical segment of the right Femur was osteotectomized, and then fixed with an 8-hole dynamic-compression plate. The animals were divided into two groups; Group A (n=12) control group and group B (n=12) PRP group. All dogs were euthanized at 2, 4, 8 and 12 weeks. The operated femurs were harvested and the implantation site were assessed for bone healing by clinical, radiographical and histological examinations. It was found that, osteoid bridging the gap at femur defect was noted in all specimens in the PRP groups at week 8 and 12 while, in control group there was a minimal periosteal reaction at the bony edges of the defect. In conclusion PRP increased bone healing at early stage 
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<br/><br/><label>Subjects--Index Terms: </label>Dogs  Femoral bone defect healing  Platelet rich plasma (PRP)