Rasha Mahmoud Hassan Rashied  <br/><br/>
Design and synthesis of novel triphenylethylenes with diverse biological activities /  
 تصميم و تشييد نظائر جديدة ثلاثية الفينيل ايثيلين ذات أنشطة بيولوجية متنوعة 
Rasha Mahmoud Hassan Rashied ; Supervised Ashraf Hassan Abadi , Nermin Salah Ahmed  
 - Cairo :   Rasha Mahmoud Hassan Rashied ,   2017 
 - 205 Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chamistry 
<br/><br/> Tamoxifen (TAM), a non-steroidal triphenylethylene SERM, is considered to be the firstline endocrine therapeutic agent used for treating ER- positive breast cancer. It reduces the risk of recurrence and death when used as adjuvant therapy in early stage or in metastatic cancer