Mahmoud Saeed Sayed Ahmed Zaid

Correlation between retinal nerve fiber layer thickness and clinical grading of optic disc edema / العلاقة بين سمك طبقة الألياف العصبية بالشبكية والتدريج الإكلينيكي لإرتشاح العصب البصري Mahmoud Saeed Sayed Ahmed Zaid ; Supervised Zeinab Saad Eldeen Elsanabary , Eman Ahmed Zaki Elbanhawy , Mostafa Ali Elhelw - Cairo : Mahmoud Saeed Sayed Ahmed Zaid , 2018 - 83 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology

The retinal nerve fiber layer (RNFL) is composed of retinal ganglion cell (RGC) axons. The peripapillary RNFL, in particular, comprises all nerve fibers entering the optic nerve disc. Therefore, evaluating the peripapillary RNFL is useful in detecting RGC damage and in understanding the pathophysiology of neuro-ophthalmic disease. Thickness of the peripapillary RNFL is a useful measure, and recent advances in diagnostic equipment allow for noninvasive measurement of RNFL thickness (RNFLT)⁽¹⁾Optical coherence tomography (OCT) is a noninvasive, high-resolution imaging technique to measure total retinal thickness, retinal nerve fiber layer (RNFL) thickness, and optic nerve head morphology. Optical coherence tomography (OCT) is a potential tool to quantify changes in the degree of optic disc edema and to monitor the efficacy of treatment interventions. OCT is a cross-sectional imaging technique that quantitatively assesses multiple layers of the retina, allowing measurement of the retinal nerve fiber layer (RNFL) thickness with a resolution of approximately 5 microns with spectral domain SD-OCT⁽²⁾



Optical coherence tomography (OCT) Retinal ganglion cell (RGC) Retinal nerve fiber layer (RNFL)