Hazem Bashir Ibrahim Mahmoud Khaliel <br/><br/>
Dexmedetomidine versus midazolam for conscious sedation during stapedectomy under local anesthesia /  
 مقارنة عقارى الديكساميديتوميدين والميدازولام فى التهدئة الوعييية اثناء استئصال عظيمة الاستابس تحت مخدر موضعى 
Hazem Bashir Ibrahim Mahmoud Khaliel ; Supervised Afaf Ahmed Mohamed Abdallah , Mona Hossameldin Abdelhamid , Tamer Mousaad Abdelhamid Gamal Eldin 
 - Cairo :   Hazem Bashir Ibrahim Mahmoud Khaliel ,   2018 
 - 188 P. :   charts , facsimiles ;   25cm  
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anesthesia 
<br/><br/> Abstract Procedural sedation can provide more comfort for the patient and an easier procedure for the clinician for painful or unpleasant diagnostic or therapeutic procedures. It might be preferred over general anesthesia due to physiological, financial and logistical considerations.  Midazolam is one of the classic sedatives for procedural sedation. While midazolam is thought to cause minimal hemodynamic effects, it does have the potential to cause loss of airway reflexes, respiratory depression, and even apnea. Dexmedetomidine (Precedex) was utilized for procedural sedation in pediatric and adult patients. It is an alpha2-adrenergic agonist that provides sedation, anxiolysis, hypnosis, analgesia, and sympatholysis. Clonidine, another alpha2 agonist, has been shown to decrease anesthetic requirements and thus prompted the study and creation of this drug  
<br/><br/>
<br/><br/><label>Subjects--Index Terms: </label>Conscious sedation  Dexmedetomidine  Midazolam