TY  - BOOK
AU  - Mohammed Ezzat Mohammed Draz
AU  - Adel Saber Lashien , 
AU  - Ahmed Sayed Saad , 
AU  - Hala Elsayed Zaazaa , 
TI  - Analytical study of some selected drugs containing nitrogen / 
PY  - 2018///
CY  - Cairo : 
PB  - Mohammed Ezzat Mohammed Draz , 
KW  - Cyclizine hydrochloride
KW  - Meclozine  hydrochloride
KW  - Pyridoxine hydrochloride
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD
N2  - Multicomponent formulations have gained a lot of importance nowadays due  to greater patient acceptability, increase potency, multiple action, and quick  relief. Simultaneous estimation of drugs in combination is an important part  in the field of pharmacy as it avoids time of extraction, separation and gets  accurate and precise results.  This concept was applied in some combinations of drugs used to treat nausea  and vomiting in pregnancy like Pyridoxine HCl, Cyclizine HCl, and  Meclozine HCl besides to Ritodrine HCl which used to arrest premature  labor.  Analysis of process-related impurities is very important in the  pharmaceutical industry. The possibility of side and toxic effects, and  reduced activity of the active substances must be reduced to a minimum. For  this reason, different analytical techniques were developed for determination  of the studied drugs in presence of their impurities. Aim of the work Development of rapid, economic, and selective methods for the  analysis of the cited drugs in raw materials and in their  pharmaceutical formulations without interference from their additives  and impurities.  Adoption as possible ecofriendly analytical methods as alternative to  reported methods for determination of the studied drugs. Validation of the newly developed procedures according to ICH  guidelines and application of the selected methods of analysis for  determination of the studied drugs in their pharmaceutical dosage forms and biological fluids
UR  - http://172.23.153.220/th.pdf
ER  -