Ahmed Fawzy Mahmoud Hamouda <br/><br/>
Immunohistochemical and histopathological study of alk and c-kit expression in bronchogenic carcinoma /  
 دراسة كيميائية نسيجية مناعية لتعبير ألك وسي كيت فى سرطان الرئة  
Ahmed Fawzy Mahmoud Hamouda ; Supervised Samira Mahmoud Abdallah , Moustafa Mohammed Samy , Lobna Omar Alfarouk   
 - Cairo :   Ahmed Fawzy Mahmoud Hamouda ,   2018 
 - 147 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pathology 
<br/><br/> This study aims to correlate immunohistochemical expression of Alk and c-kit with pathological features of lung carcinoma, and to correlate immunohistochemical expression of Alk with immunohistochemical expression of c-kit in lung carcinoma.The material of this study consists of paraffin blocks of sixty cases of patients with bronchogenic carcinoma, collected from private labs where their copies of their pathology reports were available (From January 2016 to December 2017). Immunohistochemical staining for each case was conducted for both Alk and c-kit. As regards Alk expression, 3 (5%) cases showed positive expression of Alk and 57 (95%) cases showed negative expression of Alk. As regards C-kit expression, 4 (6.7%) cases showed positive expression and 56 (93.3%) cases showed negative expression of C-kit.Among the study group, there is a significant association between expression of both Alk and c-kit and tumor histological type. Expression was notably significant among adenocarcinomas and small cell carcinomas  
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<br/><br/><label>Subjects--Index Terms: </label>Alk  c-kit  Lung cancer