Effect of transcranial direct current stimulation combined with constraint-induced movement therapy on cortical reorganization and functional outcome in stroke patients /
التأثير المزدوج للتيار المباشر عبر الجمجمة و العلاج الحركى المستحث بالتقييد على إعادة تنظيم القشرة المخية و الناتج الوظيفى فى مرضى السكتة الدماغية
Noura Abdelhamid Ahmed Elkafrawy ; Supervised Abdaleem Abdalfattah Atteya , Waleed Talat Mansour , Amani Mahmoud Nawito
- Cairo : Noura Abdelhamid Ahmed Elkafrawy , 2018
- 142 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Physical Therapy - Department of Physical Therapy for Neuromuscular and Neurosurgery
Background: The brain has an intrinsic capacity to compensate for structural damage through reorganizing of surviving networks. These processes are fundamental for recovery of function after stroke. Objectives: To investigate the combined effect of bihemispheric transcranial direct current stimulation (tDCS) and constraint induced movement therapy (CIMT) on cortical reorganization and functional recovery of the affected upper extremity in chronic stroke patients. In addition, it assessed the correlation between changes of ipsilesional cortical excitability as a measure of reorganization and functional improvements post intervention. Methods: Forty stroke patients with age ranged from 45 to 60 years were randomly assigned to receive 10 consecutive sessions of either 1) bihemispheric tDCS with simultaneous CIMTor 2) sham stimulation with simultaneous CIMT. Outcome measures include changes in fugl-meyer upper extremity motor assessment (FMUE), Motricity Index (MI) and Action Research Arm Test (ARAT). Cortical excitability of pre and post intervention was assessed using motor evoked potential (MEP) amplitude to identify neural correlates of functional improvement
Constraint induced movement therapy Stoke Transcranial direct current stimulation