TY  - BOOK
AU  - Shimaa Ahmed Abdelbaki 
AU  - George Abdelmalak Habib , 
AU  - Mohamed Youssef Salah Mattok  , 
AU  - Rafik Tawfik Mohamed Soliman , 
TI  - Preparation of horse polyvalent antiserum against rhodococcus equi and evaluation of its therapeutic and  prophylactic efficacy / 
PY  - 2018///
CY  - Cairo : 
PB  - Shimaa Ahmed Abdelbaki , 
KW  - ELISA
KW  - Polyvalent antibodies
KW  - Rhodococcus equi
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology; Issued also as CD
N2  - Rhodococcus equi, a Gram-positive facultative intracellular pathogen, is among the most widely recognized causes of  pneumonia in foals. Several antimicrobial drugs are effective against R. equi in vitro; however, many of these agents are  ineffective in vivo because of the capability of R. equi to  survive and replicates in macrophages. The present study aimed to prepare R. equi-specific hyperimmune horse antiserum and to evaluate its therapeutic and prophylactic efficacy against R. equi infection. Four horses were immunized with a locally prepared formalin inactivated R. equi vaccine adjuvanted with mineral oil. Each of these horses was immunized with 3 doses of the prepared vaccine (3ml/ dose) at  2 weeks intervals. One week after the last vaccination dose, serum from immunized horses was collected by plasmapheresis. The measured titer of R. equi specific antibodies reached to 104 ELISA units/ml after 2 weeks from  the primary immunization and up to 105 ELISA units/ml one  week after the third immunization dose
UR  - http://172.23.153.220/th.pdf
ER  -