TY  - BOOK
AU  - Hisham Ali Hammed Elshoky
AU  - Maha Anwar Ali , 
AU  - Mohamed Hassanin Gaber , 
AU  - Taher Ahmed Salah Eldin , 
TI  - In vitro localization of nanomaterials using biophysics techniques for biological evaluation / 
PY  - 2018///
CY  - Cairo : 
PB  - Hisham Ali Hammed Elshoky , 
KW  - Cytotoxicity
KW  - Localization
KW  - Nanoparticles
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics; Issued also as CD
N2  - Nanotechnology covers all fields and is applied in industrials, biological and environmental areas. Nanoparticles have several application, such as gene and drug delivery, due to their biocompatibility. We have chosen to synthesis and asses gold (GNPs), chitosan (CS), graphene oxids (GO) and zinc oxide (ZnO) nanoparticles to represent totally different sorts on nanomaterials. Nanoparticles are currently produced by wet chemistry, humers' modified method, ionic gelation method, and the sol-gel method. Here, we synthesized and characterized GNPs, GO, CS, ascorbate CS (AsCS) and ZnO nanoparticles and modified forms of ZnO and investigated their cytotoxic effects, intemalization, and distribution within the human colon carcinoma cell line using confocal laser scanning microscopy CLSM. GNPs and GO show biocompatibility at high concentration and when inter cells it does not enter the nucleus because of the size of the sheets of GO and GNPs encompasses a negative charge
UR  - http://172.23.153.220/th.pdf
ER  -