TY - BOOK AU - Mohamed Kamal Nazeer Mohamed AU - Walid Atef Ebied , AU - Wessam Gamal Eldin Abousenna , TI - Evaluation of a shorter duration prophylactic antibiotic protocol in the treatment of bone and soft tissue tumours / PY - 2019/// CY - Cairo : PB - Mohamed Kamal Nazeer Mohamed , KW - Bone and soft tissue KW - Prophylactic antibiotic KW - Short duration N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Orthopedic Surgery; Issued also as CD N2 - Background: Surgical site infection, especially in surgeries for musculoskeletal tumors, poses a considerable challenge for the orthopedic surgeon. The challenge stems from the high incidence of infection complications encountered after the reconstruction methods include allografts, tumor endoprostheses, and allograft-prosthetic composites. Aim: To evaluate the effectiveness and difference of short duration and long duration antibiotic prophylaxis in minimizing infection rate after bone and soft tissue tumor surgery. Materials and methods: A prospective randomized control trial study was conducted involving 76 patients divided into two groups. Each group divided into two subgroups; subgroups of benign tumor group (B group) and subgroups of malignant tumor (M group). The patients received preoperative prophylactic antibiotic dose of cefoperazone-sulbactam and re-dosing in case of blood transfusion or / with operative duration exceeding 3 hours, and then received postoperative doses of cefoperazone-sulbactam according to randomly selected groups and patients clinically followed-up for three months postoperatively UR - http://172.23.153.220/th.pdf ER -