TY  - BOOK
AU  - Reham Salah Eldin Sherif Saleh
AU  - Ehab Marouf Attalla , 
AU  - Wael M. Elshemey , 
TI  - Risk of secondary malignancies after radiation therapy / 
PY  - 2019///
CY  - Cairo : 
PB  - Reham Salah Eldin Sherif Saleh , 
KW  - 3D-CRT
KW  - CSI
KW  - IMRT
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics; Issued also as CD
N2  - Introduction: Despite the increasing interest in the study of the risk of radiation-induced secondary cancer in pediatric patients, the available studies are confined to either limited number of patients and/or genders or utilize only a single risk estimation approach. The aim of this study is to estimate the risk of radiation-induced secondary cancer in Craniospinal (CSI) pediatric patients  treated routinely using 3-Dimensional Conformal Radiotherapy (3D-CRT) for different ages and genders using three different risk estimation parameters. The study also aims at comparing the risk of secondary cancer for a selected sample treated using both 3D-CRT and Intensity Modulated Radiotherapy (IMRT). Methods: Sixty CSI pediatric patients are divided into 6 groups, 3  groups containing 30 males of ages of 5, 10 and 15 years and 3 groups containing 30 females of the same ages. The risk of radiation-induced secondary cancer for those patients due to 3D-CRT is estimated by calculating 3 risk estimation parameters: Excess Relative Risk (ERR), Excess Absolute Risk  (EAR) and Lifetime Attributable Risk (LAR). The risk of radiation-induced secondary cancer due to 3D-CRT is compared to that due to IMRT for a selected sample of patients (10 CSI pediatric male patients at the age of 10 years)
UR  - http://172.23.153.220/th.pdf
ER  -