Detection of cardiomyopathy in Egyptian children and adolescents with longstanding obesity /
التشخيص المبكر لمرض اعتلال عضلة القلب فى الاطفال والبالغيين المصريين المصابين بمرض السمنة المفرطة
Hala Abdelfattah Abdelkarim Mahmoud Elshennawy ; Supervised Mona Hassan Hafez , Fatma Ahmed Fathy , Antoine Fakhry Abdelmassih
- Cairo : Hala Abdelfattah Abdelkarim Mahmoud Elshennawy , 2019
- 207 P. : charts , fscsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Introduction: Obesity is considered as a strong risk factor for cardiovascular morbidity and mortality. Obesity affects the structure and function of the heart mainly by causing increased blood volume, elevated cardiac output, left ventricular (LV) hypertrophy, and LV diastolic dysfunction. all of which also play a role in causing heart failure. Objective: This cross-sectional study aimed to evaluate effect of longstanding obesity on cardiac function resulting in cardiomyopathy which may progress to heart failure in children and adolescents, to relate the level of plasma NT-Pro BNP biomarker to their echocardiographic findings and to compare these values to apparently healthy normal controls. Subjects and methods: A total of 80 obese children and adolescents who met the inclusion criteria were included in our study and 30 non obese healthy group matched for age and sex were taken as a control group regarding NT-pro BNP level, tissue velocity imaging and speckled tracking echocardiography finding