Prevalence of celiac Disease in Egyptian children with Iron deficiency anemia /
انتشار مرض الاضطرابات الهضمية في الاطفال المصريين الذين يعانون من فقر الدم بسبب نقص الحديد
Kholoud Mohamed Attia Elwakeel ; Supervised Ayman Emil Eskander , Abdel Rahman A. Abdelrazek , Marwa Mahmoud Elsharkawy
- Cairo : Kholoud Mohamed Attia Elwakeel , 2019
- 163 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Background: Celiac disease (CD) is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individuals. Iron-deficiency anemia (IDA) is the most commonly encountered anemia in humans. IDA also is a common extraintestinal manifestation of CD. Aim of work: To estimate the prevalence of CD in Egyptian children with IDA and to compare the hematologic parameters in IDA patients with and without CD. Patients and methods: A cross-sectional prospective study conducted on 382 children with IDA recruited from Cairo University Childrens Hospital outpatient clinics (Gastroenterology, Hematology, and General clinics) over a period of 21 months. Patients with chronic disease and other types of anemia were excluded from our study. The age of the study group ranged between 18 months-14 years. Patients included were subjected to full history taking, clinical evaluation, anthropometric measurements, and screened for CD by anti-tissue transglutaminase antibody immunoglobulin A (tTG IgA) and total IgA. Upper gastrointestinal endoscopy was recommended to patients who had positive serology