Lamiaa Mohammed Meghawery Matter <br/><br/>
Possible role of amiodarone versus propranolol in treatment of chronic theophylline toxicity in rats /  
 الدور المحتمل للاميودارون مقابل البروبرانولول فى علاج سمية الثيوفيلين المزمنة فى الجرذان 
Lamiaa Mohammed Meghawery Matter ; Supervised Elsayed Mahmoud Elrokh , Hisham Attia Alshekhepy , Ghada Farouk Saleh 
 - Cairo :   Lamiaa Mohammed Meghawery Matter ,   2019 
 - 155 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology 
<br/><br/> Background and aim : Theophylline toxicity continues to be a major clinical problem with potentially fatal cardiac and neurological complications .Therefore, the development of agents that have different mechanisms of action and can be used in combination with currently approved medications for the treatment of theophylline poisoning is highly desirable. Objectives: This experimental study was designed to investigate the potential role of amiodarone, the well-known antiarrythmic drug in treatment of chronic theophylline poisoning. Propranolol (non selective B-blocker) is used as a standard drug for comparison. The study was extended to show the potential anticonvulsant and theraputic effect of amiodarone against gastric erosions which occurs with theophylline poisoning  
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<br/><br/><label>Subjects--Index Terms: </label>Amiodarone  Chronic  Theophylline