TY  - BOOK
AU  - Laila Sulaiman Saleh Bashuqair
AU  - Dina Hesham Ahmed Soliman , 
AU  - Ghada Sayed Mahmoud , 
AU  - Magdy Abdelhamid , 
TI  - Elevated NT-pro BNP plasma level as a marker of acute and sub-acute ventricular affection in breast cancer patients receiving chemotherapy / 
PY  - 2019///
CY  - Cairo : 
PB  - Laila Sulaiman Saleh Bashuqair , 
KW  - Breast cancer
KW  - LV dysfunction
KW  - NT-BNP plasma level
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology; Issued also as CD
N2  - Background: Chemotherapeutic agents used for treatment of breast cancer have many side effects, among them is cardiomyopathy. Despite that ejection fraction (EF) is a widely accepted echocardiographic method, yet it fails to detect subtle alterations of LV function. There comes a need for a more sensitive tool for detection of preclinical chemotherapy-induced cardiomyopathy. Purpose: Detection of preclinical LV systolic and/or diastolic dysfunction, using NT-BNP plasma level in breast cancer patients within 6 weeks after the initiation of their chemotherapeutic treatment.  Methods: Seventy-four non-metastasizing breast cancer female patients with no cardiovascular risk factors were included. They were assessed right before taking their first chemotherapeutic session and 6 weeks thereafter. Assessment included age, two-dimensional (2D) as well as three-dimensional (3D) echocardiography. Blood samples for NT-BNP plasma level were collected before and 6 weeks after the initiation of chemotherapy. Samples were later analyzed using a Sandwich ELISA technique
UR  - http://172.23.153.220/th.pdf
ER  -