TY  - BOOK
AU  - Elham Abdelmonsef Sultan 
AU  - Antoine Fakhry Abdelmassih , 
AU  - Fatma Alzahraa Mostafa Gomaa , 
AU  - Reem Mahmoud Badr Eldeen , 
TI  - Study of PDA in preterm infants in tertiary neonatal intensive care unit : : Prevalence, complications and management / 
PY  - 2019///
CY  - Cairo : 
PB  - Elham Abdelmonsef Sultan  , 
KW  - Echocardiograph
KW  - Patent Ductus Arteriosus
KW  - Preterm
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Background: Patent ductus arteriosus poses diagnostic and therapeutic dilemma for clinicans, diagnosis of persistent PDA and determination of its clinical and hemodynamic significance are challenging. Method: Prospective observational study of 152 neonates with gestational age {u2264} 34 weeks in which clinical parameters (prenatal: maternal risk factor, use of corticosteroid, mode of delivery. perinatal: gestational age, birth weight, Apgar score, gender. postnatal: heart rate, wide pulse pressure, blood pressure, oxygen therapy, blood gases, lactate level. outcomes; sepsis, apnea, NEC,IVH,BPD, pulmonary haemorrhage and echocardiographic parameters(duct size, left atrium /aortic ratio).the clinical and echocardiographic parameters analyzed were considerd statistically significant when P<0.05. Result: In the 152 neonates, the incidence of PDA was 87 (57.2%): (54(62.1%) non HSPDA and 33(37.9%) HSPDA) that received medical treatment (paracetamol 15mg/kg/6hr IV for 3 days) follow up Echo done at day 7 of life showed 20(68,9%) cases after 1st course,4 died before the day of follow up, 9 cases received 2nd course paracetamol. follow up Echo showed 4(13.7%) cases closed, 5 cases failed closure assigned for surgical ligation. the group of non HSPDA show spontaneous closure after conservative treatment. no PDA group was 65 (42.8%) that showed 2 reopened PDA.co-morbidities such as sepsis, pulmonary hemorrhage significantly associated to PDA and HSPDA groups. mortality was higher in HSPDA group than non HSPDA group
UR  - http://172.23.153.220/th.pdf
ER  -