TY - BOOK AU - Dina Ibrahim Elsayed Ahmed AU - Ahmed Mohamed Elnahhas , AU - Samia Abdelrhman Abdelrhman , TI - Effect of whole body vibration on bone density in children with downsyndrome : : A systematic review / PY - 2019/// CY - Cairo : PB - Dina Ibrahim Elsayed Ahmed , KW - Bone mineral content KW - Bone mineral density KW - Down syndrome N1 - Thesis (M.Sc.) - Cairo University -Faculty of Physical Therapy - Department of Growth and Development Disorders in Pediatrics; Issued also as CD N2 - studies that assessed the effectiveness of whole body vibration on bone mineral density in children with Down syndrome. Methods: This review included only the published randomized controlled trials.A search was made in PubMed, Cochrane library, PEDro and Google scholar; from the earliest date to June 2019. The quality of included studies was assessed by PEDro scale. Intervention: Whole body vibration on children with Down syndrome from birth until age of eighteen years. Outcome Measures: bone mineral density. Results: Only two fair-quality studies met the inclusion criteria.Meta-analysis done and findings are presented quantitatively due to homogeneity of the studies. The mean difference across of all studies is -0.43 (95 % CI -0.98- 0.11). According to Modified Sackett Scale, there is level 2 evidence to support the use of whole body vibration to increase bone mineral density. Conclusion: The current level of evidence to support the effectiveness of whole body vibration on bone density in children with Down syndrome is still weak ER -