Efficacy and safety of fractionated microneedle radiofrequency versus botulinum toxin-A in primary axillary hyperhidrosis : A randomized controlled clinical trial /
كفاءة و أمان استخدام التثقيب المجزأ المتردد حراريا مقارنة بسم البوتيولينم أ فى علاج مرضى زيادة إفراز العرق الأولى من منطقة الإبط : تجربة عشوائية إكلينيكية مقارنة
Reem Osama Mohamed ; Supervised Eman Shaarawy Mohamed , Rehab Aly Hegazy , Vanessa Galal Hafez
- Cairo : Reem Osama Mohamed , 2019
- 112 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Vererology
Baground: Primary axillary hyperhidrosis (PAH) is an idiopathic disorder that creates severe social and psychological stress due to the production of excessive uncontrolled sweating. Various therapeutic agents have been described for PAH but each has its own limitations. The use of fractional microneedling radiofrequency (FMR) has emerged lately with promising results. Objects: To determine the efficacy and safety of FMR in comparison to Botulinum toxin (BT) in patients with PAH. Methods: In this randomized controlled clinical trial, 20 patients (40 sides) were randomized to either BT or FMR, where each side received one of the treatment modalities. BT injection was performed as a single session while FMR therapy was performed as 4 sessions, with 3 weeks interval between each. Follow up was done at 3, 6 and 12 months and the methods of assessment were Minors starch iodine test, HDSS score, Hqol questionnaire, patient satisfaction and monitoring of side effects