TY - BOOK AU - Reem Osama Mohamed AU - Eman Shaarawy Mohamed , AU - Rehab Aly Hegazy , AU - Vanessa Galal Hafez , TI - Efficacy and safety of fractionated microneedle radiofrequency versus botulinum toxin-A in primary axillary hyperhidrosis : : A randomized controlled clinical trial / PY - 2019/// CY - Cairo : PB - Reem Osama Mohamed , KW - Botulinum toxin KW - Hyperhidrosis KW - Sweating N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Vererology; Issued also as CD N2 - Baground: Primary axillary hyperhidrosis (PAH) is an idiopathic disorder that creates severe social and psychological stress due to the production of excessive uncontrolled sweating. Various therapeutic agents have been described for PAH but each has its own limitations. The use of fractional microneedling radiofrequency (FMR) has emerged lately with promising results. Objects: To determine the efficacy and safety of FMR in comparison to Botulinum toxin (BT) in patients with PAH. Methods: In this randomized controlled clinical trial, 20 patients (40 sides) were randomized to either BT or FMR, where each side received one of the treatment modalities. BT injection was performed as a single session while FMR therapy was performed as 4 sessions, with 3 weeks interval between each. Follow up was done at 3, 6 and 12 months and the methods of assessment were Minor{u2019}s starch iodine test, HDSS score, Hqol questionnaire, patient satisfaction and monitoring of side effects UR - http://172.23.153.220/th.pdf ER -