Huda Ibrahim Suliman Hegazy <br/><br/>
Role of serum (1,3)-Ý-D-glucan assay in early diagnosis of invasive f ungal infection in pediatric intensive care unit /  
 دور مادة (3,1) -بيتا- د -جلوكان فى التشخيص المبكر للعدوى الفطرية الغازية فى وحدة الرعايه المركزة للأطفال 
Huda Ibrahim Suliman Hegazy ; Supervised Hala Mohammed Fouad , Hebat Allah Fadel Elgebaly , Doaa Mohammed Ghaith 
 - Cairo :   Huda Ibrahim Suliman Hegazy ,   2020 
 - 95 P. :   charts , facsimiles ;   25cm  
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics 
<br/><br/> This study shows that critically ill children are at high risk of developing invasive fungal infection in a pediatric intensive care unit. Delaying the appropriate antifungal treatment of Invasive Candidiasis (IC) while awaiting blood culture results has been associated with increased hospital mortality.  The Candida score is a useful tool to differentiate critically ill patients, who would benefit from early antifungal treatment (score >3), from those in whom invasive candidiasis is highly improbable (score 3). One of the developed biomarkers is (1,3)-Ý-D-Glucan (BG), which is a major cell wall component of almost all fungi except for Zygomycetes and Cryptococcus species.  Various studies measured different sensitivity and specificity of (1,3)-Ý-D-Glucan (BG)substance  
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<br/><br/><label>Subjects--Index Terms: </label>Children  Mortality   Pediatric intensie care unit (PICU)