Enhanced catalytic activity of metal oxide nanocomposites for microwave assisted click reactions /
تعزيز النشاط التحفيزى لمتراكبات أكسيد المعادن النانوية لتفاعلات النقر بمساعدة الميكرويف
Hanaa Yehia Abdalluh ; Supervised Yasser Attia , Yasser Mahmoud Ali Mohamed
- Cairo : Hanaa Yehia Abdalluh , 2019
- 112 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - National Institute of laser Enhanced Sciences (NILES) - Department of Laser Application in Environmental Metrology Photochemistry Agriculture
The conventional synthetic method of 1,2,3-triazoles is [3+2]-dipolar cycloaddition between alkynes and organic azides, which generally provides a mixture of 1,4- and 1,5-regio-isomers. The most important developments were achieved in this area by the copper catalyzed azidealkyne cycloaddition (CuAAC) to obtain the 1,4-disubstituted isomer. In this study, CuO nanoparticles (NPs) and CuO/NiO nanocomposites (NCs) were synthesized with the aim of achieving [3+2] cycloaddition of organic azides with terminal alkynes under microwave irritations. The reaction showed in all cases the exclusive formation of the 1,4-isomer.The results reveled that that the CuO/NiO NCs showed potential catalytic performance than CuO NPs. This strategy features the use of microwave irradiation resulted in short reaction time, high yielding products, and selectivity. Therefore, it was expected that the as-prepared CuO/NiO nanocatalyst is a promising catalytic system for click reaction