TY  - BOOK
AU  - Mohamed Adel Sayed Mahmoud 
AU  - Dalia H. Soliman , 
AU  - Sahar M. Abouseri , 
AU  - Samar H. Fahim , 
TI  - Design and synthesis of certain novel benzenesulfonamide derivatives with anticancer activity / 
PY  - 2020///
CY  - Cairo : 
PB  - Mohamed Adel Sayed Mahmoud , 
KW  - Anticancer
KW  - Benzenesulfonamide derivatives
KW  - Cancer
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD
N2  - Cancer is one of the leading causes of death across the world, causing great  stress to human life. Chemotherapy emerged to be important key player in the  treatment of many of cancer patients ranging from primary to advanced stages.  However, the severe side effects, poor tolerance and the development of resistance to  chemotherapeutic drugs limited their use in many patients. Therefore, the  development of novel, efficient, and less toxic anticancer agents remains a serious  and challenging goal for the medicinal scientists worldwide.  One of the most powerful discovered anticancer scaffolds is the  benzenesulfonamide moiety attached to triazole or pyrazole rings. Therefore, the  present study deals with the synthesis of different series of benzenesulfonamides  hybridized with triazoles, fused triazoles and fused pyrazoles either through direct  connection or via azo (-N=N-) spacer furnishing
UR  - http://172.23.153.220/th.pdf
ER  -