TY  - BOOK
AU  - Rania Abdelfattah Mousa  
AU  - Dina Metwally Salama , 
AU  - Rana Fathy Helal , 
TI  - Comparative study for treatment of alopecia areata using carboxytherapy, intralesional steroids or both together / 
PY  - 2020///
CY  - Cairo : 
PB  - Rania Abdelfattah Mousa , 
KW  - Alopecia areata
KW  - Intralesional  steroids
KW  - Intralesional carboxytherapy
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology; Issued also as CD
N2  - Background: Alopecia areata (AA) is a commonly encountered  autoimmune hair loss disorder with multifactorial etiology. Although  steroids are considered the first line of treatment in AA, they cannot alter the course of the disease. Intralesional carboxytherapy (ILC) induces a  state of relative hypercapnia with increased blood flow with the potential  to treat AA. Aim of the study: To compare the efficacy, safety, and longevity of ILC,  intralesional steroids, and their combination, during treatment and at the  end follow up period. Methods: This study is a randomized interventional comparative clinical  trial conducted on 30 patients with patchy AA. For every patient, each  patch was randomized to receive intralesional steroid, ILC, or a  combination of both. Every patient received six sessions, two weeks apart  over three months. Patients were assessed before treatment, one week after the last session, and at the end of the follow-up period using the newly introduced modified severity of alopecia tool (M.SALT) score and  dermoscopic assessment. Abstract Results: The different treatment modalities showed measurable improvement and hair regrowth with a statistically significant increase in  percentage improvement of M.SALT score at the end of follow up period compared to both before and after treatment in the areas treated with intralesional steroid compared to ILC
ER  -