Hanaa Adel Saied Tailab <br/><br/>
Oxidative stress and antioxidant status in neonatal sepsis /  
 الاجهاد التاكسدي ومضادات الاكسدة في الاطفال حديثي الولاده المصابين بميكروب في الدم 
Hanaa Adel Saied Tailab ; Supervised Dalia Ahmed Saied , Marwa Abdelhady Abdelsamad , Doaa Mohamed Abdo 
 - Cairo :   Hanaa Adel Saied Tailab ,   2020 
 - 154 P . :   charts ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics 
<br/><br/> Background: Septicemia is a major threat to survival during the early stages of life . It remains a major cause of morbidity and mortality in  neonates. Pathophysiology of neonatal sepsis is complex,multifactorial,oxidative stress and antioxidant imbalance plays an important role.  Aims: to assess the alteration in serum antioxidant level in neonatal sepsis.  Methods: This is a prospective case-control study. It has been conducted on one hundred  neonates recruited from  the neonatal  intensive care unit,Cairo  university hospitals.The neonates were divided into two groups: Seventy septic neonates of both sexes, preterm or fullterm at any postnatal age (clinically and/or laboratory) proved sepsis  and thirty healthy aseptic neonates age and gender matched as controls. Sepsis was  scored  according  to  the  hematologic  scoring  system(Rodwell  score). Serum creatine phosphokinase, albumin and uric acid  levels were  done on chemistry autoanalyzer (Beckman Coulter), glutathione peroxidase by colorimetric method on spectrophotometer ultraspectro (pro3100) 
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<br/><br/><label>Subjects--Index Terms: </label>Antioxidants Neonatal sepsis Oxidative stress marker