Effect of elliptical trainer on lipid profile, oxidative stress indicators and antioxidant status in diabetic women type 2 /
تأثير التمرين المغزلى على دهون الدم و مؤشرات الإجهاد التأكسدى و حالة مضادات التأكسد لدى مريضات السكر النوع الثانى
Alyaa Abdallah Altallah Ahmed Zeid ; Supervised Zahra Mohamed Hassan Serry , Hany Ezzat Obaya , Hoda Ibrahim Fahim
- Cairo : Alyaa Abdallah Altallah Ahmed Zeid , 2020
- 127 P . : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Physical Therapy - Department of Physical Therapy for Cardiopulmonary and Geriatrics Disorders Thesis (M.Sc.) - Cairo University - Faculty of Physical Therapy - Department of P.T for Cardiovascular- Monary & Geriatrics Disorder
Background: There is a strong relationship between hyperglycemia, oxidative stress (OS) caused by hyperglycemia, systemic inflammation, and type 2 diabetes mellitus (DM) development and progression. Objective: The aim of this study was to find out the response of lipid profile, OS indicators and antioxidant status to elliptical trainer (ET) in diabetic women type 2. Method: The study was done on 60 diabetic type 2 women with ages ranged from 40-50 years old and body mass index (BMI) varied from 30-34.9 kg/m2. All patients were randomly assigned to two equal groups in number. The study group (n = 30) received 40-minute aerobic exercise on ET - 3 times weekly for 16 weeks in addition to home walking program for 30 minutes day after day out of exercise session day while the control group )n= 30) received hypoglycemic drug only. Fasting blood glucose, homeostasis model assessment of insulin resistance, glycosylated hemoglobin A protein test, lipid profile [serum concentrations of total cholesterol, triglycerides, high density lipoprotein-cholesterol (HDL-c), non-HDL-c, lipoprotein phospholipase enzyme, pro-inflammatory markers [tumor necrosis factors-alpha and interleukin-6], malondialdehyde (OS marker), and antioxidants as erythrocyte superoxide dismutase and reduced glutathione were measured before and after the study period. Results: The study group showed a highly statistical significant difference in all measures while the control group revealed no significant statistical improvement in any measure. Conclusion: ET decreased the insulin resistance, hyperglycemia, dyslipidemia, systemic inflammation, and OS in addition to the increase of antioxidants