TY  - BOOK
AU  - Amal Mostafa Sayed Mostafa
AU  - Amal Hassan Abdelrahman , 
AU  - Reham Salah Hamed , 
TI  - Immunohistochemical expression of cyclooxgynase-2 and transforming growth factor-Ý1 in adenoid cystic carcinoma of salivary gland : : In vitro study / 
PY  - 2018///
CY  - Cairo : 
PB  - Amal Mostafa Sayed Mostafa , 
KW  - Cyclooxgynase-2
KW  - Factor-Ý1
KW  - Salivary gland
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology; Issued also as CD
N2  - The aim of the present study was to investigate the immunohistochemical expression of TGF-Ý1 and COX-2 in different variants of ACC (cribriform, tubular/trabecular and solid) and also correlate the expression of the two markers with each other. A total of 30 specimens were collected. The standard avidin-biotinperoxidase technique has been used in the present study for detection of TGF- Ý1and COX-2, the immunostaining of these markers were evaluated by an image analyzer computer system. The study demonstrated that COX-2 and TGF-Ý1expression was significantly increased in solid variant of ACC than other patterns and thus concluded that COX-2 and TGF-Ý1expression are directly related to ACC histopathological grade. The study also showed a significant direct correlation between the immunostaining of TGF-Ý1 and COX-2.In most of cases the increase in COX-2 expression is associated with increase in TGF-Ý1expression, which may indicate that TGF-Ý1 induce the expression of COX-2
UR  - http://172.23.153.220/th.pdf
ER  -