Outcome of thoracic primitive neuroectodermal tumors in pediatrics : A single-institution experience /
دراسة استرجاعية لنتائج علاج الأطفال المرضى بأورام الصدر للغدد العصبية البدائية بالمعهد القومى للأورام . مصر
Mona Ahmed Moustafa Elsaudi ; Supervised Hossam Eldeen Ahmed Abdelmonem , Ahmed Mohammed Kamel , Ibrahim Abdelrahman Ibrahim
- Cairo : Mona Ahmed Moustafa Elsaudi , 2021
- 119 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric (Oncology)
Background:Primitive neuroectodermal tumors (PNETs) are malignant and aggressive 2small round cells3 neoplasms that arise from the primitive nerve cells of the central nervous system (central PNETs), but at times, they can affect any peripheral nerve (peripheral PNETs) in the neck, chest wall, retroperitoneum, pelvis, and extremities (Khmou et al., 2016). In 1979, Askin et al. described for the first time, 20 cases of children and adolescents affected by PNETs of the thoracopulmonary region.Since then,PNETs developed within the soft tissue of the thoracopulmonary region are referred to as 2Askins tumors3 [AT] (Triarico et al., 2018).In addition to this, Askins tumors occur typically in children and adolescents and they belong to the Ewings sarcoma (EW) family because of their histological, immunohistochemically, cytogenetic, and phenotypic similarities (Parikh M et al., 2011).Because of the rarity of this neoplasm, the approach to Askins tumors is complex and it may require a multidisciplinary management (Devi LP et al., 2015)