TY - BOOK AU - Alzahraa Rabei Attia Ibrahim AU - Ahmed Samir Mohamed , AU - Khaled Abdelaziz Abdelmoein , TI - Bacteriological studies on some multidrug resistant pathogens isolated from different animals and their effect on public health / PY - 2021/// CY - Cairo : PB - Alzahraa Rabei Attia Ibrahim , KW - Companion animals KW - MRSA KW - Multi-Drug resistant bacteria N1 - Thesis (M.Sc) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology; Issued also as CD N2 - Nowadays, companion animals as cats, dogs and horses have frequently considered family members and close animal contact occurs daily. Therefore, the transmission of a variety of microorganisms that cause diseases, like multidrug-resistant pathogens between animals and owners has increased and has become a public health issue. Accordingly, the purpose of this study was to investigate the transmission of antibiotic resistant bacteria between companion animals and humans, and more specifically the role of companion animals in transmission of methicillin-resistant Staphylococcus aureus (MRSA) and extended spectrum beta-lactamase (ESBL) to humans in varying degrees of contact with these animals. Here, carriage of methicillin-resistant Staphylococcus aureus (MRSA) and extended spectrum beta-lactamase (ESBL) producing bacteria in companion animals was assessed. Nasal and rectal samples were cultured on chromogenic media and MaCconkey agar in addition to 0.2 mg cefotaxime directly for detection of MRSA and ESBLs, respectively. Considering MRSA detection; nasal swabs were collected from 134 companion animals with respiratory illness (48 horses,41 dogs and 45 cats). All swabs were cultured for MRSA using MRSA CHROMagar medium, whereas isolates were identified as MRSA after colonial morphology, biochemical tests Gram staining, coagulase test, resistance to cefoxitin and detection of mecA gene. Moreover, antimicrobial resistance patterns for all obtained MRSA isolates were determined by the disk diffusion method. The prevalence rates of MRSA among horses, dogs and cats were 8.3%, 2.4% and 0% respectively ER -