TY  - BOOK
AU  - Reem Mohamed Mahmoud Ramdan Abdelkareem
AU  - Mortada Hassan Elshabrawi , 
AU  - Ola Omar Shahin , 
AU  - Sherif Ramzy Baroudy , 
TI  - Health related quality of life in children with crigler- najjar syndrome / 
PY  - 2020///
CY  - Cairo : 
PB  - Reem Mohamed Mahmoud Ramdan Abdelkareem , 
KW  - Crigler- najjar syndrome (CNS)
KW  - Health related quality of life in children
KW  - Hepatitis quality of life questionnaire (HRQOL)
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Aim of work:1- To assess HRQOL among pediatric patients with CNS and correlate it with the severity of the disease. 2- Assessment the cognitive functions in patients with CNS. Patients and methods:  Cross- sectional observational study for all cases diagnosed with CNS typy1. HRQOL was assessed by using World Health Organization Quality Of Life BREF questionnaire (WHOQOL-BREF) for cases and the study short form-36(SF-36).The cognitive functions was assessed by Stanford{u2013}Binet Intelligence Scale: Fifth Edition (SB5). ResultsThe mean ±SD age of the patients was 5.48 ± 3.44 years. Eleven of them were females (57.1%), the other of them nine were males (42.9%) with age ranging between 1 to 18 years. No statistically significant difference was detected between cases and regards rural or urban residence or social level.The primary presented symptom was jaundice being present in sixteen (76.2%) of cases had mild degree of jaundice as a clinical presentation, three of them (14.3%) had skin pigmentation and five (23.8%) of them had neurological affection as a complications with no other system affection.  The disease was chronic & non-curable. Sixteen (76.2%) of cases were diagnosed at the first month of life, twenty-one (100%) of cases had history of NICU admission, only five (32.8%) of cases had history of exchange transfusion as results of hyperbilirubinemia, only ten (47.6%) of cases had a compliance on phototherapy as a treatment
ER  -