Polymorphism of genes involved in susceptibility to acute lymphoblastic leukemia /
التنوع فى الجينات المتورطة فى القابلية لحدوث مرض سرطان الدم الليمفاوى الحاد
Eman Roshdy Radwan ; Supervised Azza Mostaf ibrahim Mostafa , Iman Maher Mansour
- Cairo : Eman Roshdy Radwan , 2006
- 100p : ill ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
Human linear chromosomes terminate with telomeres consisting of tandemly repeated DNA sequences and several binding proteinsBecause of the end replication problem , telomeric sequences are lost with each cell divisionTelomerase is ribonucleoprotein reverse transcriptase enzyme complex that almost all cancer cells acquired to stabilize telomere length and extend their life - spanMeasurement of telomere length and telomerase activity might be useful to monitor disease condition in haematological neoplasias