TY - GEN AU - Eman Roshdy Radwan AU - Azza Mostaf ibrahim Mostafa , AU - Iman Maher Mansour , TI - Polymorphism of genes involved in susceptibility to acute lymphoblastic leukemia / PY - 2006/// CY - Cairo : PB - Eman Roshdy Radwan , KW - Haematological neoplasias KW - Telomerase enzyme KW - Telomeres N1 - Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology; Issued also as CD N2 - Human linear chromosomes terminate with telomeres consisting of tandemly repeated DNA sequences and several binding proteinsBecause of the end replication problem , telomeric sequences are lost with each cell divisionTelomerase is ribonucleoprotein reverse transcriptase enzyme complex that almost all cancer cells acquired to stabilize telomere length and extend their life - spanMeasurement of telomere length and telomerase activity might be useful to monitor disease condition in haematological neoplasias UR - http://172.23.153.220/th.pdf ER -