TY  - GEN
AU  - Abdalwali Ahmad Saif Hameed
AU  - Mohamed Sayed Ahmed ElSamaligy , 
AU  - Omaima Naeem ElGazayerly , 
TI  - Formulation and dvaluation of a low dissolution drug in soft gelatin capsules with solubilized and emulsified core adjuvants / 
PY  - 2005///
CY  - Cairo : 
PB  - Abdalwali Ahmad Saif Hameed , 
KW  - Capsules
KW  - solubilized
N1  - Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutics; Issued also as CD
N2  - Many drugs have limited bioavailability due to either the influence of the physiological factors associated with the structure and function of GI tract , or the physicochemical properties of the drug and dosage form factorsAs the drug should be soluble to be absorbed , one of the methods to increase the drug availability is to deliver it in solution dosage formMany of the old drugs and most of the outcome new molecules have limited solubilityThe need to manipulate drug's poor solubility is essential to reach the desired solution concentrationSolubilization methods are : cosolvency , micellar solubilization , complexation , pH control , hydrotropy and solid dispersion , chemical modification , crystal modification and particle size reduction
UR  - http://172.23.153.220/th.pdf
ER  -