Synthesis and pharmacological evaluation of 1-Benzyl and 1-Benzoyl melatonin analogs as ligands for melatonin receptors / Amal Mahmoud Yassin Mohsen ; Supervised Darius P. Zlotos
Material type:
- تشييد وتقييم بيولوجى ل ن 1 بنزايل و ن 1 بنزويل من مشتقات الميلاتونين كلجائن لمستقبلات الميلاتونين [Added title page title]
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2010.Am.S (Browse shelf(Opens below)) | Not for loan | 01010110060246000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
The neurohormone melatonin (MLT) exerts its diverse physiological actions mostly through activation of the two G-protein-coupled MT₁ and MT₂ receptors . An accurate characterization of MLT receptor-mediated functions requires MT₁ and MT₂ selective ligands . One of the most selective MT₂ antagonists up to date is the p - chlorobenzl substituted indole derivative UCM 454
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