Added value of Elastography for Evaluation of breast masses detected on screening ultrasound / Doaa Ahmed Eltayeb Mohamed ; Supervised Soha Talaat Hamed , Marwa Anas Abdelrahman , Ahmed Mohamed Farahat

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Background: the major limitation of screening Breast US is substantial increase in the number of false-positive findings. Objective: was to evaluate the additional value of Elastography and to determine an appropriate guideline for the combined assessment of screening US detected breast masses. Patient & methods: an observational cross-sectional study that included 35 patients (with 39 breast lesions). Ultrasound Elastography (qualitative and quantitative) was performed following screening breast ultrasound. Sensitivity, specificity, accuracy and predictive values for both modalities were calculated. Results: US elastography was more sensitive and specific in differentiating benign from malignant lesions and decreasing numbers of unnecessary biopsies. The calculated sensitivity of combined ultrasound and elastography was 100%, specifity 94.4%, PPV 94.4% , NPV100% and the total accuracy 92.7% compared to 100%, 90.5%, 90%, 100% and 94.9% for US alone respectively. Qualitative elastography is more accurate which increase the specifity from 90.5% to 100%. Conclusion: US Elastography provides useful information about distinguishing benign and malignant lesions. Thus, consideration of lesion stiffness could increase positive predictive values and reduce unnecessary benign biopsies. The elastography is better to be done qualitative and quantitative as the qualitative is more specific than the quantitative

Issued also as CD