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Analysis of some fluoroquinolone drugs via reaction with organic and inorganic reagents using different analytical tools / Heba Ali Dakhly Ali ; Supervised Mohamed Abdelgawad Zayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Heba Ali Dakhly Ali , 2015Description: 190 P. : charts ; 25cmOther title:
  • تحليل بعض أدوية الفلوروكينولون من خلال التفاعل مع بعض الكواشف العضوية وغير العضوية باستخدام وسائل التحليل المختلفة [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry Summary: To develop and validate simple, rapid and selective spectrophotometric methods for micro-determination of Gemifloxacin mesylate (GMF), Moxifloxacin.HCl (MXF), Gatifloxacin sesquihydrate (GAF) and Ciprofloxacin.HCl (CPF) drugs in pure and in pharmaceutical preparations through the ion-pair formation reaction with Rose Bengal Disodium Salt (Rb) and iron (III) hexathiocyanate (FSN) reagents in aqueous media. 2- To prepare, separate and elucidate the structures of solid ion-pairs of Gemifloxacin mesylate, Moxifloxacin.HCl, Gatifloxacin sesquihydrate with Rose Bengal reagent by the elemental analysis and (FT-IR and 1H-NMR) spectroscopic techniques. 3- To describe the importance of combination of several analytical techniques (FT-IR and 1H-NMR) in elucidating the structures of solid ion-pairs of GMF, MXF, and GAF with Rb reagent. 4- To investigate the biological activity of these drugs in comparison with their prepared solid ion-pairs with Rb
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.08.M.Sc.2015.He.A (Browse shelf(Opens below)) Not for loan 01010110067561000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.08.M.Sc.2015.He.A (Browse shelf(Opens below)) 67561.CD Not for loan 01020110067561000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry

To develop and validate simple, rapid and selective spectrophotometric methods for micro-determination of Gemifloxacin mesylate (GMF), Moxifloxacin.HCl (MXF), Gatifloxacin sesquihydrate (GAF) and Ciprofloxacin.HCl (CPF) drugs in pure and in pharmaceutical preparations through the ion-pair formation reaction with Rose Bengal Disodium Salt (Rb) and iron (III) hexathiocyanate (FSN) reagents in aqueous media. 2- To prepare, separate and elucidate the structures of solid ion-pairs of Gemifloxacin mesylate, Moxifloxacin.HCl, Gatifloxacin sesquihydrate with Rose Bengal reagent by the elemental analysis and (FT-IR and 1H-NMR) spectroscopic techniques. 3- To describe the importance of combination of several analytical techniques (FT-IR and 1H-NMR) in elucidating the structures of solid ion-pairs of GMF, MXF, and GAF with Rb reagent. 4- To investigate the biological activity of these drugs in comparison with their prepared solid ion-pairs with Rb

Issued also as CD

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