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Detection of CD44 in candidal leukoplakia and smokers keratosis / Mai Taha Mohammed Abo Omar ; Supervised Nagwa Othman , Olfat Gameel Shaker , Eman Mohammed Amro

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mai Taha Mohammed Abo Omar , 2014Description: 131 P. : photographs ; 25cmOther title:
  • فى طلوان الفم البيضاء و التقران المصاحب للتدخين CD44 الكشف عن دلاله الاورام [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology Summary: The aim of this study was to detect level of salivary CD44 in oral smoker{u2019}s keratosis (SK) and candidal leukoplakia (CL) and correlate it with epithelial dysplasia and the possibility of malignant transformation. This study was performed on a total of 35 patients divided into 3 groups; 15 patients having SK lesions, 5 patients having candidal CLlesions and 15 healthy control individuals. The levels of CD44 were measured in the saliva of all patients and controls by ELISA Kits and correlated with the presence or absence of epithelial dysplasia in both lesions. There was a statistically significant difference (p < 0.001) between mean value of salivary sCD44 (22.17 ng / ml ( ± 7.52)) in the SK group and that of the control group (10.034 ng / ml ( ± 2.30)). The CL group showed a statistically significant difference (p < 0.001) between the mean level of salivary sCD44 and that of the control. There was no statistically significant difference (p < 0. 388) between the mean level of salivary sCD44 amongst SK and CL group. It was found that there was an increase in the dysplastic changes among groups with more mean value of sCD44
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.08.M.Sc.2014.Ma.D (Browse shelf(Opens below)) Not for loan 01010110067869000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.08.M.Sc.2014.Ma.D (Browse shelf(Opens below)) 67869.CD Not for loan 01020110067869000

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology

The aim of this study was to detect level of salivary CD44 in oral smoker{u2019}s keratosis (SK) and candidal leukoplakia (CL) and correlate it with epithelial dysplasia and the possibility of malignant transformation. This study was performed on a total of 35 patients divided into 3 groups; 15 patients having SK lesions, 5 patients having candidal CLlesions and 15 healthy control individuals. The levels of CD44 were measured in the saliva of all patients and controls by ELISA Kits and correlated with the presence or absence of epithelial dysplasia in both lesions. There was a statistically significant difference (p < 0.001) between mean value of salivary sCD44 (22.17 ng / ml ( ± 7.52)) in the SK group and that of the control group (10.034 ng / ml ( ± 2.30)). The CL group showed a statistically significant difference (p < 0.001) between the mean level of salivary sCD44 and that of the control. There was no statistically significant difference (p < 0. 388) between the mean level of salivary sCD44 amongst SK and CL group. It was found that there was an increase in the dysplastic changes among groups with more mean value of sCD44

Issued also as CD

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