Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Obesity in children and adolescents has become an increasing clinical and public health concern. Its prevalence has increased significantly worldwide with an alarming rise of its co - morbidities. The excess of visceral adipose tissue is associated with hypertension, prothrombotic and pro-inflammatory states leading to cardiovascular diseases. Fibrinogen, which is a key player in the coagulation cascade, promotes atherogenesis, and is an independent risk factor for CVD. To find possible associations between visceral obesity and plasma fibrinogen, as one of the hemostatic factors, in obese children. Our study included 43 obese children and 40 non-obese age and sex matched children who were taken as controls. Both groups were subjected to a detailed history taking, complete physical examination, anthropometric assessment, and body composition analysis, ultrasonography measurement of visceral adipose tissue and subcutaneous fat and laboratory measurement of plasma fibrinogen

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