Pharmacological study of the possible antiulcerogenic effect of certain natural substances extracted from different medicinal plants / Rania Mohamed Rahmo ; Supervised Sanaa A. Kenawy , Laila G. Mahran , Dalaal M. Abdallah
Material type:
- دراسة دوائية للتأثير المضاد للقرحة المتوقع حدوثه باستعمال مواد طبيعية مستخلصة من بعض النباتات الطبية [Added title page title]
- Issued also as CD
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.09.Ph.D.2013.Ra.P (Browse shelf(Opens below)) | Not for loan | 01010110061640000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.09.Ph.D.2013.Ra.P (Browse shelf(Opens below)) | 61640.CD | Not for loan | 01020110061640000 |
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
A major clinical problem encountered with the use of indomethacin (IMN),a Non-steroidal anti-inflammatory drug, is gastrointestinal complications. It was reported that IMN develops gastropathy by inducing reactive oxygen species(ROS)as well as pro-inflammatory mediators such as tumor necrosis factor Ü (TNF-Ü). Moreover, IMN induced peptic ulcer (PU) by inducing apoptotic death, manifested by an increase in the expression of Cyt c and caspase-3
Issued also as CD
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